App Profile: ICD10 Diseases Classifications

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ICD-10-CM (Medical Coding) is the official system of assigning codes to diagnoses and procedures associated with hospital utilization in the United States.

CDC released the FY2025 ICD-10-CM with 252 new codes, 36 code deletions, and 13 code revisions making the cut, going into effect on October 1, 2024.

Key Features:

Index of Drugs and Chemicals
Index of Diseases and Injuries
Index of External Causes of Injuries
Index of Neoplasm
The National Center for Health Statistics (NCHS) and the Centers for Medicare and Medicaid Services are the U.S. governmental agencies responsible for overseeing all changes and modifications to the ICD-10-CM.

Highlights from the new 2025 ICD-10-CM codes

ICD-10 codes for cancer in remission
The neoplasm chapter contains codes for most benign and all malignant neoplasms. Chapter 2 - Neoplasms leads the way this year in the quantity of new codes, receiving .63 new codes expanding cancer to include ""in remission.""

C81.1A Nodular sclerosis Hodgkin lymphoma, in remission
C81.2A Mixed cellularity Hodgkin lymphoma, in remission
C81.3A Lymphocyte depleted Hodgkin lymphoma, in remission
C82.5A Diffuse follicle center lymphoma, in remission
C82.6A Cutaneous follicle center lymphoma, in remission

Updates to ICD-10 codes for Hypolycemia and Obesity
Chapter 4 – Endocrine, nutritional and metabolic diseases adds level and class to Hypolycemia and Obesity.

E16.A2 Hypoglycemia level 2
E16.A3 Hypoglycemia level 3
E66.81 Obesity class
E66.811 Obesity, class 1
E74.82 Disorders of citrate metabolism
E74.820 SLC13A5 Citrate Transporter Disorder
E74.829 Other disorders of citrate metabolism

ICD-10 codes for mental health disorders
In the 2025 update of ICD-10-CM, Chapter 5 – Mental and Behavioral Disorders adds type and severity to eating disorders and 2 new codes for mental and behavioral conditions in adults.

F50.010 Anorexia nervosa, restricting type, mild
F50.023 Anorexia nervosa, binge eating/purging type, extreme
F50.21 Bulimia nervosa, mild
F50.814 Binge eating disorder, in remission
F50.83 Pica in adults
F50.84 Rumination disorder in adults

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Publisher: Centers for Disease Control and Prevention